FLEXIBLE INITIATION METHOD
This nomogram is useful in hospitalized patients in whom INR
can be checked on a daily basis.
Several studies have confirmed that 5mg initiation achieves
therapeutic anticoagulation as rapidly as 10mg initiation but with a
lower frequency of supra-therapeutic INRs.
The 10mg initiation nomogram should only be used in relatively young
and healthy patients who are likely to be insensitive to warfarin,
or in patients taking concurrent medications known to induce
warfarin metabolism. Please note that
loading doses of warfarin are NOT RECOMMENDED.
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